Billy Gardell as Officer Mike Biggs
Melissa McCarthy as Molly Flynn
Reno Wilson as Officer Carl McMillan
Rondi Reed as Peggy Biggs
Swoosie Kurtz as Joyce Moranto
Louis Mustillo as Vince Moranto
Katy Mixon as Victoria Flynn
Nyambi Nyambi as Samuel
Suzie Q as Jim the dog
Cleo King as Rosetta McMillan
David Anthony Higgins as Harry